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Research interest from institutions across the Ireland has grown rapidly alongside the broader global expansion of metabolic peptide research

Badve SV, Bilal A, Lee MMY et al (2025) Effects of GLP-1 receptor agonists on kidney and cardiovascular disease outcomes: a meta-analysis of randomised controlled trials

Research pioneer Dr

The potential molecular pathways that can be targeted include IL-4-IL-13-JAK-STAT-MAP kinases, adiponectin-iNOS-NF-B, PGD2-CRTH2, IFNs-RIG, Wnt/-catenin-FAM13A, FOXC1-miR-PI3K/AKT, JNK-Gal-7, Nrf2-ROS, Foxp3-RORt, CysLTR, AMP, Fas-FasL, PTHrP/PPAR, PAI-1, FcRI-LAT-SLP-76, Tim-3-Gal-9, TLRs-MyD88, PAR2, and Keap1/Nrf2/ARE

111 have led to a series of well-characterized inhibitors