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At this volume, even a 2-unit measurement error represents nearly 10% dose variation
One limitation of most PK and PD studies is the enrollment of healthy subjects, whereas the major target population for use of GLP1RAs are patients with diabetes and obesity who may have co-morbidities that might affect the PK results
The spending limit typically caps at $2,000, though this can increase over time with consistent on-time payments
Then they think, Maybe it was too weak, and take another one
doi: 10.1038/s41586-023-05856-5 164 HuangZ.SrinivasanS.ZhangJ.ChenK.LiY.LiW.et al
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