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Ionics 28 , 34773488 (2022)

Methyl B12 has many functions: Helps methylation

Weindel CG, Martinez EL, Zhao X, Mabry CJ, Bell SL, Vail KJ, et al

These changes may explain why some people report pain or discomfort from things that normally wouldnt hurt, like clothing, bedsheets, or light touch

Other possibilities include diverticular disease, inflammatory bowel disease, colorectal polyps or cancer, and medication-related bleeding from concurrent use of anticoagulants, antiplatelet agents, or NSAIDs