Deficiency is common in those with fatigue, brain fog, or nutrient absorption issues, especially individuals with gastrointestinal conditions, vegans and vegetarians, or those taking medications like metformin or proton-pump inhibitors
Oral dosing keeps plasma ascorbate below roughly 220 micromoles per liter (mol/L), whereas controlled IV infusion can safely **generate** pharmacologic concentrations of 2530 millimoles per liter (mmol/L)a finding documented by Mark Levines National Institutes of Health group in Vitamin C pharmacokinetics: implications for oral and intravenous use (Padayatty and colleagues, Annals of Internal Medicine, 2004)
GMP CERT
Differences in maternal care during the first 6 days of life in a mammal can cause different methylation patterns in some genes
PubMed: 11297605 AOD 9604 Stimulates Bone Formation and Increases Bone Mineral Density in Osteoporotic Rats animal Shen Y, Hurvitz SA, Paige D, et al