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Based on preclinical (animal and cellular) data only, inhibition of NNMT by 5-Amino-1MQ is theorised to: Raise intracellular NAD+ levels Activate SIRT1 and other sirtuins (proteins linked to metabolic regulation) Reduce fat cell (adipocyte) size and proliferation Improve insulin sensitivity These effects have been demonstrated in mouse models (Neelakantan et al., 2019), but robust human clinical trial data are currently absent

After exploring options with a functional medicine provider, Alex began a short cycle of 5-Amino-1MQ, paired with moderate resistance training and a high-protein diet

Subcutaneous Injections A less invasive option, with benefits typically noticeable within a day or two

Always communicate with your provider

Your doctor will determine the appropriate schedule based on your specific condition and response