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Before your appointment, ensure you are well-hydrated and have eaten a light meal

This may be explained by the findings of Albares and colleagues, Guinot and colleagues, and Kang and colleagues , who reported that pregnancy, use of hormonal contraception and lack of use of sunscreen are aggravating factors of melasma due to increase number and activity of melanocyte in epidermis

Golden MH, Jackson AA, Golden BE

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Phase 2: Days 16-30 (2 mg/day) From day 16 onward, the dose doubles to 8 units (2 mg per injection)