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The plasma level of the natural peptide GHK (which forms GHKCu) averages about 200 ng/mL at age 20 and falls to around 80 ng/mL by age 60, tracking with reduced tissue repair and collagen support in older skin [7]
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For subcutaneous versus intramuscular research dosing considerations, see our breakdown on subcutaneous and intramuscular peptide injection, which covers needle gauge and depth recommendations relevant to reconstituted peptide delivery
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This often smooths out side effects, though it doubles injections
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