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Pregnenolone from Selye to Alzheimer and a model of the pregnenolone sulfate binding site on the GABAA receptor
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The collapse of both astrocyte and microglia into pro-inflammatory states due to depletion of GSH, leading to sustained neuroinflammation and oxidative stress, is observed in many neurodegenerative diseases (Ferreira et al., 2013
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This roughly matches normal skin pH
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