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The MHRA ( Medicines and Healthcare products Regulatory Agency ) has two main application procedures: Simple Reclassification : This is a straightforward and quick procedure based on an analogous product (a medicinal product already on the UK market with the same active ingredient, route of administration, use, and a similar or higher strength/dosage)

A prolonged, untreated deficiency can cause nerve damage that may become permanent

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Additionally, the lack of stomach acid increases the amount of bacteria that use B12, making less of the vitamin available for the body to use