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They work by: Slowing gastric emptying , which prolongs feelings of fullness Reducing appetite through effects on brain centres that regulate hunger Improving insulin secretion and glucose metabolism Potentially reducing food intake and affecting eating behaviours These injections are administered subcutaneously, typically once weekly (semaglutide) or once daily (liraglutide), and have been approved by the MHRA for weight management in adults with a BMI 30 kg/m, or 27 kg/m with weight-related comorbidities, as an adjunct to reduced-calorie diet and increased physical activity

To our knowledge, this is the first Mendelian randomization study to assess the associations between GLP-1RAs and these psychiatric conditions

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It mimics one hormone (glucagon-like peptide-1) that targets the brain to reduce appetite and slows down stomach emptying, making you feel full longer

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