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Patients require a maintenance dose of GLP-1s to sustain their weight, Apovian explains

Others need several treatments

Ipamorelin is often praised for its selectivity and low impact on cortisol and prolactin

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These medications have long half-lives (the time it takes for the amount of a drug's active substance in your body to reduce by half), so starting a new treatment too soon can: Increase the risk of side effects, Reduced effectiveness Overlap drug activity, making unclear which drug is causing which reaction, and the new therapys true effects may be masked