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Serious side effects are rare but can include hormonal imbalance (especially in women with PCOS or PCOD) and severe allergic reactions

doi:10.1016/s0928-4257(97)89480-6

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Insert the needle through the KLOW stopper, angle it toward the inside glass wall, and let the water run down the side instead of forcing it directly onto the powder

Panel B shows the GSH regulatory motif (taken from Figure 1), including the effects of estradiol and the inhibition of GCL and glutathione synthetase (GS) by GSH