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However, long-term use of ghrelin appears to promote weight gain and decrease glucose tolerance

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Human sleep studies also show that shortened sleep can affect gut hormones involved in satiety, including GLP-1 in some groups

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doi: 10.1016/j.tifs.2024.104847 133

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GLP-3-A Game Changer in Obesity Pharmacotherapy, Katsi V

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If hunger becomes unmanageable during a reduction step, pause the taper for 12 extra weeks before advancing to the next lower dose

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