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A new safety signal emerged: dysesthesia (abnormal sense of touch) affected 20.9% of patients on the highest dose, though it was generally mild
Fusobacterium nucleatum induces MDSCs enrichment via activation the NLRP3 inflammosome in ESCC cells, leading to cisplatin resistance
The reason for this divergent outcome may lie in a specific hydrogen-bonding network, Thr---Asp---H 2 O, that is present in the canonical PDO active site but missing in CstB (Fig
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