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Advances and challenges in the treatment of lung cancer

In conclusion, we show that chronic in vivo GSH deficiency, despite inducing CYP2E1 and hepatic oxidative stress, triggers adaptive mechanisms that protect the liver against ethanol-induced toxicity

Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state

While our study primarily targeted antioxidant markers, future investigations should integrate assessments of pro-oxidants and oxidative markers to elucidate the complete oxidative balance in OCP users