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In a substudy of 178 patients from the SUSTAIN 8 trial on semaglutide as a diabetes treatment, the average proportion of lean mass loss was nearly identical at 40%, despite lower doses and less total weight loss than in the STEP 1 trial

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This suggests that the supplement may help the body clear the toxic byproduct faster than it would on its own

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Diabetes Care 37 , 13841391 (2014)

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Although statistically significant, these effects remain smaller than those achieved with retinoids or growth factor formulations

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