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Additionally, - glucans have a very minimal probability of having any unfavorable side effects and are reasonably inexpensive

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Using various biochemical and biophysical approaches, we demonstrate that Syn WT engages in functional interactions, whereas C-terminal acidic tail truncated Syn 1103 and S129-phosphomimicking ( S129E ) mutant are reactive, displaying broad, non-functional aberrant binding and impairing chaperone-mediated refolding

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