One of the most common issues people face is GLP-1 constipation
As in the previous recommendations by the ADA and EASD (73, 74), life-style intervention (with patient education and motivation, increase of physical activity, and healthy eating) is still in the beginning and center of therapy, followed by pharmacological therapy with metformin (7074)
Ahmadi F, Etemadi SM, Lessan-Pezeshki M, Mahdavi-Mazdeh M, Ayati M, Mir A, Yazdi HR
Some people find they tolerate fiber supplements better when taken with a meal
These next-generation agents may address some current limitations while potentially introducing new challenges