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Study Findings Although waist circumference, hip circumference, BMI, and weight significantly decreased in both groups , the only significant difference between the two groups was in waist circumference reduction

Side Effects Gastrointestinal symptoms: Most common adverse effects were mild-to-moderate nausea, vomiting, and diarrhea, occurring primarily during dose escalation [6] [12]

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While this metabolic effect supports weight management, the primary driver of GLP-1mediated weight loss is reduced calorie intake rather than a substantial increase in energy expenditure

Trial teams are required to provide participants with 24-hour contact details for safety concerns