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Although preclinical models have yielded promising resultsfor example, the histone deacetylase inhibitor WW437 and the RNA helicase EIF4A inhibitor Zotatifinthese findings have not yet translated effectively into clinical application, largely due to species-specific differences between human and animal models, as well as a lack of robust clinical data [356, 357]

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Yamada T, Sato S, Sotoyama Y, Orba Y, Sawa H, Yamauchi H, et al

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BPC-157 oral capsules are typically taken once or twice daily, often on an empty stomach for optimal absorption, though timing can be adjusted based on individual digestive patterns and therapeutic goals