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Changes in actin polymerization status can affect focal adhesion signaling complexes, integrin-mediated signaling, and transcriptional responses that govern cellular movement and structural adaptation

Traditional Chinese medicine and natural products possess unique advantages in simultaneously intervention on multiple modes of RCD (131, 176, 177, 194, 202)

In the 50s, when chemotherapy wasnt yet available, massive doses of B12 shots were given to children with a neuroblastoma tumor every two days, for 2-3 years with great success: NEUROBLASTOMA: AN EVALUATION OF ITS NATURAL HISTORY AND EFFECTS OF THERAPY, WITH PARTICULAR REFERENCE TO TREATMENT BY MASSIVE DOSES OF VITAMIN B12

Its a systems-based approach

*Correspondence: Prashant Shukla, [email protected], [email protected]