Understanding How GLP-1s Work During Fasting GLP-1 medications continue working 24/7, including during fasting hours
doi:10.1002/(SICI)1096-9861(19990111)403:2 3.0.CO;2-5 116
Iranpoor N, Jafari-Gharabaghlou D, Abdulzehra S, Dashti MR, Gorbanzadeh F, Zarghami N
The phase 3 RCT of oral semaglutide add-on therapy evaluating the efficacy and safety of oral semaglutide in T2D subjects with moderate renal impairment (PIONEER-5) 49 demonstrated significantly greater HbA1c improvement compared with placebo of 0.8% and weight reduction of 2.5 kg
One pattern that shows up in community discussions is that people who track their measurements (waist, hips, chest, arms) in addition to their weight tend to notice changes earlier than scale watchers