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We recommend discussing NAION risk with healthcare providers before starting GLP-1 therapy
10.1002/prot.25234 86 YanY.ZhangD.ZhouP.LiB.HuangS
GLP-1 therapy is adjusted and monitored over time based on results and tolerability
However, cases of concomitant deficiencies involving B 12 with either B 1 or B 6 remain rare, suggesting distinct risk factors and clinical presentations for each vitamin deficiency
It is engineered with two structural modifications relative to the 70-residue native protein: a substitution of arginine for glutamic acid at the third position and a 13-amino-acid extension at the N-terminus, giving a total length of 83 amino acids
