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L-Carnitine alleviates hepatic and renal mitochondrial-dependent apoptotic progression induced by letrozole in female rats through modulation of Nrf-2, cyt C and CASP-3 signaling
Although both GSTM2 -overexpressing mice and control mice showed good recovery of hepatic steatosis at 2 weeks, GSTM2 -overexpressing mice showed lower hepatic fat content at 1 week (Fig
Furthermore, low doses of the compound diallyl trisulfide, which increases expression of the antioxidant enzymes heme oxygenase1 (HO-1) and NAD(P)H quinone dehydrogenase (NQO1), protects motor neurons from toxicity induced by mutant TDP-43 Q331K and TDP-43 M337V (Liu C
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