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For individuals with higher starting weights, this is achievable with long-term treatment and lifestyle changes.

If your pain is severe, you have a high fever, or your abdomen is rigid and tender throughout, go directly to the ER

The results were published in The New England Journal of Medicine in May 2025

Author contributions TMA: Validation, Software, Writing review & editing, Formal Analysis, Writing original draft, Methodology, Data curation, Conceptualization, Investigation, Visualization

Needle anxiety is common, but research shows that proper technique and calm, controlled breathing significantly reduce pain perception during subcutaneous injections