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A 2025 case-control study from Vietnam found what researchers described as a U-shaped relationship between B12 intake and cancer risk, with both lower and higher intakes associated with increased risk
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A randomised controlled trial is considered the gold standard of clinical evidence
Pilozzi A, Carro C, Huang X (2021) Roles of -endorphin in stress, behavior, neuroinflammation, and brain energy metabolism
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