8,56,63 After binding with a ligand for a certain period, the receptor will trigger the inward sinking of the membrane, forming an endosomal compartment, which is called agonist-induced receptor internalization
So when microdosing, if your typical dose is 18 clicks on a 1 milligram pen for 0.25 milligrams, microdosing 0.05 milligrams (the lowest possible dose, per Dr
1) that enables albumin binding and prolongs the half-life
Vendelbo MH, Moller AB, Christensen B, Nellemann B, Clasen BF, Nair KS, Jorgensen JO, Jessen N, Moller N
Less common effects: Allergic skin reaction such as itching or rash