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The effect is dose-dependent and reversible (after discontinuation, pigmentation subsides over weeks to months)
The studies on digoxin did not show an effect on time in therapeutic range
declares research grants from Amgen, Bristol Myers Squibb, the Erling Persson Foundation, Novo Nordisk and the Swedish Heart Lung Foundation and lecture/consultant honoraria from Bayer, Eli Lilly and Novo Nordisk
Further translational research and prospective clinical trials are required to clarify causality, determine effect size, and identify high-risk groups most likely to benefit
Cardiovascular (CV) damage in PASC CV complications are prevalent among PASC patients since ACE2 receptor-rich cardiomyocytes provide SARS-CoV-2 direct access to the heart
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