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However, semaglutide has comprehensively surpassed exenatide in every clinical dimension: weight loss efficacy (approximately 4-5 fold greater), glycemic control (superior in SUSTAIN 3 head-to-head), cardiovascular outcomes (proven superiority vs non-inferiority), dosing convenience (pre-filled pen without reconstitution), and formulation options (oral available)
Regular check-ins and support help reinforce these changes for long-term success
Studies in elderly populations, who share some constipation mechanisms with GLP-1 users (slower transit, reduced food intake), showed significant improvements in bowel movement frequency
GLP-1s and the weight loss they drive tend to pull fat out of the liver, and ALT and AST often improve as a result
Use a broad-spectrum sunscreen with an SPF of 40 or higher every day to manage uneven pigmentation
