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Under the if-all-adhere estimand, participants on CagriSema achieved approximately 15.7% weight reduction at week 68, compared with approximately 3% for placebo

Patients develop early-onset neurological manifestations and neurodevelopmental disorders that are currently incurable ( The pathophysiological mechanisms underlying most mitochondrial diseases causing neurodevelopmental disorders are poorly understood

It's important to note that persistent symptoms can lead to further complications, such as chronic pain or arthritis, if left untreated

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