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Retatrutide is a novel triple-hormone-receptor agonist that is being investigated as a potential medication for weight loss

This is unlike fat soluble vitamins, like vitamins A, D E, and K, which will continue to get stored in the bodys fat when supplemented excessively, and can lead to side effects if over supplemented beyond the bodys needs

Tayran H, Yilmaz E, Bhattarai P et al (2024b) ABCA7-dependent induction of neuropeptide Y is required for synaptic resilience in Alzheimers disease through BDNF/NGFR signaling

A healthy body mass index lowers the risk of other health issues

Since 90% of the bodys serotonin originates in the gut, these peripheral effects could influence central serotonergic tone through vagal signaling