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Some people experience more pronounced gastrointestinal side effects as the dose increases, which is why titration matters

This is due to an excessive amount of calcified black tartar accumulated under the gum tissue, which may result in the black appearance near the gums, but the gums themselves do not have discoloration

Discontinuing tirzepatide resulted in a similar amount of weight regain

While natural presence in the body is reassuring, supplementation introduces higher concentrations than the body typically manages, which can occasionally lead to side effects, particularly in vulnerable populations or when combined with certain medications

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