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25 Reconstituted blood (washed platelets [25010 6 /mL], washed erythrocytes [Hct=40%], 100 g/mL human fibrinogen, 7.5 g/mL AF546-conjugated human fibrinogen, 2 mmol/L CaCl 2 , and 2 mmol/L MgCl 2 ) was incubated with vehicle or indicated peptide (50 nmol/L) in the presence of 7 mol/L sitagliptin for 10 minutes
Nothing prevents extending these intervals to six or even eight weeks if side effects are problematic
Developed by Eli Lilly, it is administered as a once-weekly subcutaneous injection
CGM data was used to generate ambulatory glucose profile (AGP), a 24-h glucose course
The phase 3 SUSTAIN (Semaglutide Unabated Sustainability in Treatment of Type 2 Diabetes) clinical trial program evaluated the efficacy and safety of semaglutide in subjects with T2D in a range of patient populations across the continuum of diabetes care [7,8,9,10,11,12,13,14]
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