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But, there are several reports supporting an association between inadequate B12 levels and premature hair graying, which is grey hair that onsets before the ages of 20-30 (depending on the demographic) (12)

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Individuals with certain medical conditions or allergies should avoid Tirzepatide, as well as those with a personal or family history of medullary thyroid carcinoma ( type of thyroid cancer) or multiple endocrine neoplasia type 2 (tumors in the glands)

The highest incidence occurs during the initial weeks of treatment and with each dose escalation

(PubMed) Varkal MA, Karabocuoglu M