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This damage is associated with a variety of chronic diseases and conditions

Endoxifen (4-hydroxy-N-desmethyl-tamoxifen) has anti-estrogenic effects in breast cancer cells with potency similar to 4-hydroxy-tamoxifen

Further, GPx5, the cystine (active site) containing homotetrameric enzyme, is expressed exclusively in the epididymis to protect sperms from being damaged by hydrogen peroxide during their maturation [1, 8, 9]

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In other words, its when the thyroid is underactive. For many women, the root cause of hypothyroidism is Hashimotos thyroiditis, an autoimmune condition where the body attacks its own thyroid tissue