losing weight without glp-1 GLP-1? No. 🚫💉 No medications were used for my loss. , I had someone say to me recently – “I didn’t know people were still weight the old-fashioned way.“ 🤣, Yes. They are. , I have., 182 GLP-1 for Weight Loss: Everything

Schrag M, Mueller C, Zabel M, Crofton A, Kirsch WM, Ghribi O, et al

Liraglutide (Saxenda) was one of the earlier forms of longer-lasting GLP-1s and reduces HbA1c (average blood glucose) levels by around 1.3% on average and fasting plasma glucose by 2 mmol/L

These effects are consistent with subcutaneous peptide administration generally and tend to diminish with continued use as the body acclimates to the metabolic changes

Tirzepatide has the potential benefit of improving metabolic control and cardiovascular function because of its dual activity on GIP and GLP-1 receptors

When switching to a less potent alternative, appetite may increase, making mindful eating more important