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The responsible first step in either case is testing, not guessing

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Chemical synthesis involves the step-by-step assembly of amino acids in a controlled laboratory environment, allowing for precise customization of the peptide sequences to target specific biological functions

The results showed that the majority of GFP-positive cells (237 cells from 9 embryos) were PGCs in controls ( ~93.3%), whereas the proportion was ~32% in mTmG - Trim37 ko3 embryos (185 cells from 11 embryos), with the remaining GFP + population lacking OCT4 expression (Fig