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The investigators conducted a multicenter, double-blind, placebo-controlled, active-controlled phase 3a trial (ClinicalTrials.gov ID: NCT05567796) evaluating the efficacy and safety of the combination of semaglutide and cagrilintide in adults without diabetes with a body-mass index (BMI) of greater than or equal to 30 or greater than or equal to 27 with at least one obesity-related complication

Synovial fluid LTB4 levels are upregulated in RA patients

Freezing can preserve a reconstituted peptide for six months or even longer

The peptides well-characterized in vitro effects and favorable preliminary safety profile position it well for translational investigationif undertaken with pharmaceutical-grade materials and rigorous methodology

Third-party laboratories provide unbiased verification