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It is worth noting that for currently licensed GLP-1 receptor agonists in the UK, the thyroid tumour signal is classified as a precautionary consideration based on rodent data, rather than a formal contraindication as reflected in UK Summaries of Product Characteristics (SmPCs)
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While irritability is not listed as a common side effect in clinical trials, some patients do experience mood changes
Patients should consider the financial commitment alongside potential health benefits when deciding whether to pursue private GLP-1 treatment, and check current NHS prescription charges via the NHS Business Services Authority website
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Intra-articular injections Intra-articular injection of corticosteroids and hyaluronic acid are selectively used in the treatment of OA
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