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Due to structural resemblance, it acts as a potent agonist of melanocortin receptors located in different areas of the central and peripheral nervous system

ALCAR is synthesised from L-Carnitine , which is produced from the amino acids lysine and methionine

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Another key energy sensor is AMP-activated protein kinase (AMPK), an insulin-independent regulator of glucose uptake, which on activation by exercise, regulates downstream targets involved in mitochondrial biogenesis, energy metabolism, and oxidative capacity (Ruderman et al., 2013