In addition, their impact on gastric motility has raised perioperative concerns, particularly related to delayed gastric emptying, which increases the risk of vomiting and aspiration during induction of general anesthesia
Cost considerations without insurance (as of 2025): Wegovy (semaglutide): approximately $1,300-$1,500 per month Saxenda (liraglutide): approximately $1,300-$1,400 per month Zepbound (tirzepatide): approximately $1,000-$1,200 per month These prices reflect list prices
Biologics cost $900 million more to develop than small molecules on median but generate twice the peak annual revenue and take 8 years longer for competing products to reach the market
87 KruseTHansenJLDahlKSchfferLSensfussUPoulsenCet al
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