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BPC-157 is a stable pentadecapeptide fragment originally isolated from human gastric juice by Predrag Sikiric's research group at the University of Zagreb in the early 1990s
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The GHK sequence also appears within the alpha-2(I) chain of type I collagen, leading to the hypothesis that collagen degradation at wound sites releases GHK fragments that then bind copper and signal for new collagen production, creating a self-repair feedback loop
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