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If you hear of someone dropping dead, particularly about a week after surgery or in a young healthy person, this is the number one concern

Users who run continuous high-dose protocols often report diminishing returns, while those who cycle seem to maintain consistent responses over months and years of use

However, its very unlikely that an increased bile flow removes toxins from blood: over 95% of the bile released into the small bowel reenters the liver and is recycled [51+]

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However, as oxidative stress increases, the permeability of this barrier increases, and free radicals can cross the barrier