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Comparative studies further demonstrate that plants selectively accumulate chemically optimized scaffolds rather than broadly activating secondary metabolism ( Table 2 )

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Untargeted metabolomics Liver samples The collected samples were thawed on ice, and metabolites were extracted using 80% methanol buffer

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Nevertheless, methionine-loading experiments suggest that methionine excess induced vasospasms and thrombosis (Bellamy et al, 1998