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Diabetes Care 47 , 18731888 (2024)
Practical strategies can significantly reduce nausea associated with GLP-1 receptor agonist therapy, improving treatment adherence and patient outcomes
Mimicking one of the effects of bariatric surgery, namely the increased secretion of glucagon-like peptide (GLP)-1, by artificially increasing the levels of GLP-1 might prove successful as obesity treatment
GLP1R prediction showed similarly strong performance, with classification accuracy above 90% and discrimination ability of approximately 85%
Improvement and competition is expected over time, whether by creating more modifications to improve half-life , improving access to the brain, converting existing injectable drugs into oral forms, combining with other agonists or antagonists (Molecules that prevent receptors/molecules from functioning) such as DPP-4 inhibitors, which help extend the half-life of peptides such as GLP-1 and GIP
