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Multiple in vitro studies have demonstrated that NAC actively induces the non-immunological degranulation of mast cells, causing them to dump pre-formed histamine directly into the bloodstream, which can trigger immediate allergic-type symptoms

Ingredients 200 g firm tofu 1 cup miso or ginger broth 1/2 cup shelled edamame if tolerated Cooked mushrooms or spinach Small rice portion if calories are needed Method 1

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The 2025 meta-analysis by Alfalasi and colleagues, published via PMC, synthesized data from 16 studies and 6,098 total participants