Among surviving patients, the most severely affected patients have intellectual disability, with IQs ranging from the low 50s to around 60, progressive cerebellar disease and ataxia, recurrent bacterial infections, chronic metabolic acidosis, and hemolytic anemia
2.5 Collating, summarizing, and reporting the literature We provided a brief history and rationale for the reviewing the topic, a summary of the antioxidant supplements as well as outcome measures and trend of safety and effectiveness of the antioxidant supplements
Hatzikirou H, Basanta D, Simon M, Schaller K, Deutsch A
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Standard dosing regimens using pens: Minor damage/GI health maintenance: 250-500 mcg daily (1-2 clicks), divided into two doses per day, course duration 2-4 weeks