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10,11 A rapid decay in circulation, coupled with less than 2 minutes of half-life of GLP-1 by dipeptidyl peptidase-IV (DPP-IV), caused researchers to develop GLP-1R agonists or DPP-IV inhibitors aimed at maintaining the effects of GLP-1 in pharmacological or physiological concentration, respectively

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After matching, there were no significant differences in the baseline characteristics between groups (absolute SD values 50%, and the composite renal outcomes