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The FDA declared the tirzepatide shortage resolved in 2025 and has since issued warning letters and enforcement actions against compounders and telehealth companies that marketed unauthorized or improperly compounded tirzepatide

Persistent or severe acne should be evaluated by a licensed medical provider before, during, and after any topical or oral treatment

If it does not, compare LillyDirect or equivalent self-pay paths against telehealth compounded options like Pomegranate Health

Factors influencing results include: Starting weight Metabolic health Medication adherence Protein intake Exercise habits Medical history Our goal is not rapid weight loss but sustainable weight management and improved overall health

Side effect comparison: Nausea: Similar rates between the two compounds Vomiting: Cagrilintide significantly lower (OR 0.38) Diarrhea: Comparable rates Constipation: Similar Injection site reactions: Cagrilintide substantially higher Discontinuation due to AEs: Cagrilintide much lower (1% vs approximately 5-7%) The takeaway: if vomiting was your main problem on semaglutide, cagrilintide may be worth exploring