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pancreatic damage via modulation of oxidative and nitrosative stress

The peptide is generally regarded as safe and well-tolerated, while occasionally producing minor adverse effects associated with its effect on melanogenesis.

Management approaches include increasing fiber intake gradually (too much fiber at once worsens bloating), drinking at least 64 ounces of water daily, taking magnesium citrate (400-600mg at bedtime), and increasing physical activity

Therefore, suppressing PFKFB3-driven excessive glycolysis could be a promising therapeutic strategy for pulmonary fibrosis